It is recognised that not all child longer-term outcomes will be able to be covered by a single study but the domains listed here should be covered by a set of complementary studies, which together build up a comprehensive evidence-base. It is also noted that individual measurements of offspring health and development will not be sufficient to detect nor exclude associations between in utero medication exposure and adverse health or neurodevelopmental outcomes; rather data should be collected regularly throughout childhood.
Display only CDE items recommended as ESSENTIAL when studying: Pregnancy and infant outcomes Longer term childhood outcomes
| CDE Item | Definition | Recommended data format and suggested values | Essential to collect when studying pregnancy and infant outcomes | Essential to collect when studying longer term childhood outcomes | Source | Purpose | Notes |
|---|---|---|---|---|---|---|---|
| Child cognitive functioning | The expected developmental level within the area of cognitive functioning varies by the age of the child. This should be measured via age appropriate assessment using either 1. parental completed questionnaires 2. through direct research / clinical assessment of the child or 3. Diagnoses of deficits (e.g. intellectual disability). 4. Attainment of key milestones. | Will depend on the method of collection | Yes | Yes | Directly reported | Report statistics | Includes functioning in the areas of intelligence, memory, attention and executive functioning. |
| Child motor functioning | The expected developmental level within the area of motor functioning varies by the age of the child. This should be measured via age appropriate assessment using either 1. parental completed questionnaires 2. though direct researcher assessment of the child or 3. Diagnoses of deficits relating to motor development/ functioning (e.g. dyspraxia). 4. Attainment of key milestones. | Will depend on the method of collection | Yes | Yes | Directly reported | Report statistics | |
| Child language functioning | The expected developmental level within the area of language functioning varies by the age of the child. This should be measured via age appropriate assessment using either 1. parental completed questionnaires 2. through direct research / clinical assessment of the child or 3. Diagnoses of deficits (e.g. language delay or disability). 4. Attainment of key milestones. | Will depend on the method of collection | Yes | Yes | Directly reported | Report statistics | Attainment of cognitive milestones can be used but due to normal variation in attainment times and cross-cultural differences, standardized questionnaire or assessments are more valid. |
| Child social functioning | The expected level of social functioning varies by the age of the child. This should be measured via age appropriate assessment using either 1. parental completed questionnaires 2. though direct researcher assessment of the child or 3. Diagnoses of deficits relating to social development/functioning (e.g. autism spectrum disorder). 4. Attainment of key milestones. | Will depend on the method of collection | Yes | Yes | Directly reported | Report statistics | |
| Child behaviour and emotional functioning | The expected level of behaviour and emotional varies by the age of the child. This should be measured via age-appropriate assessment using either 1. parental completed questionnaires 2. though direct researcher assessment of the child or 3. Diagnoses of deficits relating to behavioural or emotional regulation difficulties (e.g. attention deficit hyperactivity disorder, depression). 4. Attainment of key milestones. | Will depend on the method of collection | Yes | Yes | Directly reported | Report statistics |