Display only CDE items recommended as ESSENTIAL when studying: Pregnancy and infant outcomes Longer term childhood outcomes
| CDE Item | Definition | Recommended data format and suggested values | Essential to collect when studying pregnancy and infant outcomes | Essential to collect when studying longer term childhood outcomes | Source | Purpose | Notes |
|---|---|---|---|---|---|---|---|
| Family history of congenital anomalies | The presence of any congenital anomaly (major or minor) in any sibling (live born, stillborn or terminated), or the mother or the father of the reference pregnancy, or their immediate/ first degree relatives (grandparents, aunts or uncles of the reference pregnancy) | Value 1 - Options: a) Yes, b) No, c) Unknown If "Yes", Value 2 (MedDRA/ICD diagnosis code): Text If "Yes", Value 3 (Coding system) - Options: a) MedDRA, b) ICD10, c) Other (detail) - Text If "Yes", Value 4 (record details of anomaly, and relationship to the affected family member): Text |
No* | No* | Directly reported | Sub-setting Risk factor Derivation (number of previous pregnancies with congenital anomalies) |
*Not essential but highly recommended as an important co-variable risk factor. Only the categorical response can be used in data sub-setting or as a risk factor statistic. May be useful to improve analysis of infant congenital anomaly data. |
| Relevant family history of genetic conditions | The presence of any genetic condition in a relative thought to be the explanation or of relevance to the abnormalities reported in the reference pregnancy | Value 1 - Options: a) Yes, b) No, c) Unknown If "Yes", Value 2 (MedDRA/ICD diagnosis code): Text If "Yes", Value 3 (Coding system) - Options: a) MedDRA, b) ICD10, c) Other (detail) - Text If "Yes", Value 4 (record details of the condition(s), and relationship to the affected family member): Text |
No* | No* | Directly reported | Sub-setting Risk factor |
*Not essential but highly recommended as an important co-variable risk factor. Only the categorical response can be used in data sub-setting or as a risk factor statistic. May be useful to improve analysis of infant congenital anomaly data. |
| Relevant family history of learning disability or of neurodevelopmental disorders | The presence of a learning disability or neurodevelopmental disorder (e.g. attention deficit hyperactivity disorder or autistic spectrum disorder) in a sibling, mother, father or their immediate / first degree relatively (grandparents, aunts or uncles of the reference pregnancy) | Value 1 - Options: a) Yes, b) No, c) Unknown If "Yes", Value 2 (MedDRA/ICD diagnosis code): Text If "Yes", Value 3 (Coding system) - Options: a) MedDRA, b) ICD10, c) Other (detail) - Text If "Yes", Value 4 (record details of the condition(s), and relationship to the affected family member): Text |
No | No* | Directly reported | Sub-setting Risk factor |
*Not essential but highly recommended as an important co-variable risk factor. Only the categorical response can be used in data sub-setting or as a risk factor statistic. History of learning disability or neurodevelopmental disorders may be relevant to neurodevelopmental outcomes but less essential for certain childhood health variables. |
| Relevant family history of diseases with onset in childhood | The present of a health condition which onsets in childhood (<18 years of age) | Value 1 - Options: a) Yes, b) No, c) Unknown If "Yes", Value 2 (MedDRA/ICD diagnosis code): Text If "Yes", Value 3 (Coding system) - Options: a) MedDRA, b) ICD10, c) Other (detail) - Text If "Yes", Value 4 (record details of the condition(s), and relationship to the affected family member): Text |
No | No* | Directly reported | Risk factor | *Not essential but highly recommended as an important co-variable risk factor. Only the categorical response can be used in data sub-setting or as a risk factor statistic. History of health conditions may be relevant to child health conditions but less so to other longer term outcomes (e.g. neurodevelopmental outcomes) |
| Number of previous pregnancies | Number of previous pregnancies (including non-live births) experienced by the mother only | Integer | No | No | Directly reported | Risk factor | |
| Number of previous live births | Number of previous live births | Integer | No* | No* | Directly reported | Sub-setting Risk factor |
*Not essential but highly recommended as an important co-variable risk factor. May be useful to improve analysis of infant birth weight data Birth order may be particularly relevant for certain developmental outcomes |
| Number of previous spontaneous abortions | Number of previous spontaneous abortions | Integer | No* | No | Directly reported | Sub-setting Risk factor |
*Not essential but highly recommended as an important co-variable risk factor. May be useful to improve analysis of miscarriage data |
| Number of previous induced terminations | Number of previous induced terminations (for any reason) | Integer | No | No | Directly reported | Sub-setting Risk factor |
|
| Number of previous stillbirths | Number of previous stillbirths | Integer | No* | No | Directly reported | Sub-setting Risk factor |
*Not essential but highly recommended as an important co-variable risk factor. May be useful to improve analysis of stillbirth data |
| Number of previous pregnancies with congenital anomalies | Number of previous pregnancies (including non-live births) experienced by the mother which resulted in a fetus or child with congenital anomalies | Integer | No* | No | Directly reported | Sub-setting Risk factor |
*Not essential but highly recommended as an important co-variable risk factor. May be useful to improve analysis of infant congenital anomaly data |