Table 8: Pregnancy outcome details

The following CDE items should be collected for each fetus in the reported pregnancy.


Display only CDE items recommended as ESSENTIAL when studying: Pregnancy and infant outcomes Longer term childhood outcomes

CDE Item Definition Recommended data format and suggested values Essential to collect when studying pregnancy and infant outcomes Essential to collect when studying longer term childhood outcomes Source Purpose Notes
Pregnancy outcome collection status Status of pregnancy outcome details reported to the system Options: a) Outcome known, b) Follow-up pending, c) Lost-to-follow-up, d) Missing Yes Yes Internally generated (derived from reported outcome details) Dataset creation

Follow-up
Date of end of pregnancy Date at which the pregnancy completes (for all outcomes). Date (dd/mm/yyyy) Yes Yes Directly reported

Derived (gestational age at end of pregnancy and date of LMP or date of EDD)
Derivation (pro/retrospective status)

Derivation (LMP/EDD and subsequently exposure timing)

Derivation (gestational age at end of pregnancy)
For live births, this will be the date of delivery (infant date of birth).

For terminations/evacuation of retained products of conception, this will be the date the procedure was performed.
Gestational age at end of pregnancy Gestational age in days (post-LMP) at the time the pregnancy ended Integer Yes Yes Directly reported

Derived (date of end of pregnancy and date of LMP or date of EDD)
Derivation (pro/retrospective status)

Derivation (LMP/EDD and subsequently exposure timing)

Derivation (pre/postmature delivery)

Derivation (birth weight for gestational age)
Calculated as either the time since the first day of the LMP or from prenatal ultrasound scans

If necessary, converted from weeks and days (post-LMP) or weeks and days (based on prenatal ultrasound measurements)
Induced termination Induced abortion (either medical or surgical) of a pregnancy for any reason Value 1 - Options: a) Yes, b) No, c) Unknown

If, "Yes", Values 2 (reason for termination) - Options: a) Non-medical reason, b) Medical reason (maternal indication), c) Medical reason (fetal indication), d) Other, e) Unknown

If "Other", Value 3 (details): Text
Yes Yes Directly reported Report statistics
Ectopic pregnancy Implantation outside of the endometrial cavity (including tubal, cervical, caesarean scar, interstitial, cornual, ovarian, abdominal, hetertopic or of unknown location) confirmed by transvaginal ultrasound. Options: a) Yes, b) No, c) Unknown Yes Yes Directly reported Report statistics
Stillbirth Death of a fetus prior to the complete expulsion or extraction from its mother, after the 22nd completed week post-LMP (≥154 days) of pregnancy; the death is indicated by the fact that after such separation the fetus does not breathe or show any other evidence of life, such as beating of the heart, pulsation of the umbilical cord or definite movement of voluntary muscles Options: a) Yes, b) No, c) Unknown Yes Yes Directly reported Report statistics In line with EMA recommendations, this document defines stillbirth as fetal loss >22 completed weeks post-LMP.

International definitions of stillbirth vary. Some definitions rely purely on the gestational age at pregnancy loss (varying from 20 weeks post-LMP to 28 weeks post-LMP), others also consider the weight of the fetus at pregnancy loss (e.g. fetal weight >500g required to classify as a stillbirth/intrauterine death).

Definitions may require local adaptation.

Post-mortem details should be recorded where available.
Spontaneous abortion Death of a fetus prior to the complete expulsion or extraction from its mother, before the 22nd completed week of pregnancy (≤153 days). Options: a) Yes, b) No, c) Unknown Yes Yes Directly reported Report statistics See notes on stillbirth.
Molar pregnancy A non-viable product of conception which can be either a 'complete mole' arising after single sperm fertilisation of an ovum lacking genetic material, or a 'partial mole' which arises as a consequence of multi-sperm fertilisation of a healthy ovum. An invasive mole (formerly known as chorioadenoma destruens) is a hydatidiform mole that has grown into the muscle layer of the uterus Options: a) Yes, b) No, c) Unknown

If "Yes", Value 2 - Options: a) Hydatidiform Mole (complete or partial), b) Invasive Mole, c) Mole of unknown type

Yes Yes Directly reported Report statistics
Blighted ovum A non-viable pregnancy in which the embryo either never develops, or begins to develop, and is reabsorbed. Diagnosis requires ultrasound examination to establish a gestational sac diameter of >25mm with no fetal pole detected Options: a) Yes, b) No, c) Unknown Yes Yes Directly reported Report statistics
Live birth Delivery of a fetus, irrespective of the duration of the pregnancy, which after separation shows signs of life, such as beating of the heart, breathing, pulsation of the umbilical cord, or definite movement of voluntary muscles Options: a) Yes, b) No, c) Unknown

If "Yes", Value 2 - Options: a) Hydatidiform Mole (complete or partial), b) Invasive Mole, c) Mole of unknown type

Yes Yes Directly reported Report statistics