Comment on the latest meta-analysis investigating childhood neurodevelopment outcomes following acetaminophen (paracetamol) use in pregnancy

Professor Per Damkier (University of Southern Denmark), Chair of the ENTIS Scientific committee, has provided a comment on the most recent meta-analysis investigating in utero exposure to acetaminophen and childhood neurodevelopment (Ricci et al., 2023). In this comment, published in Paediatric and Perinatal Epidemiology, Prof Damkier highlights important key methodological limitations and notable conflicting findings in the primary source literature. […]

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Pregnancy and birth related experiences of postpartum women during the third wave of the COVID-19 pandemic

Researchers affiliated to the ENTIS network, led by Professor Hedvig Nordeng (University of Oslo) and Dr Michael Ceulemans (KU Leuven and Teratology Information Service Lareb), have published the results of a pan-European online questionnaire investigating pregnancy and birth related experiences of women during the third wave of the COVID-19 pandemic. More information can be found here. Photo by Alexander Grey […]

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Close of the 33rd annual ENTIS conference

Between the 8th and 10th September 2022, Dr Georgios Eleftheriou and colleagues from Poison Control Center and Teratology Information Service at the Papa Giovanni XXIII Hospital hosted the 33rd ENTIS conference in Bergamo, Italy. Engaging key note lectures were provided from internationally renown experts on a range of topics including the teratogenic risks of caffeine, risk communication and scientific misinformation, […]

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Position statement: Live vaccine use following in utero or lactation infliximab exposure

In March 2022 the European Medicines Agency’s (EMA) published a direct healthcare professional communication (DHPC) regarding the use of live vaccines in infants exposed to infliximab in utero or during breastfeeding. The DHPC stated that live vaccines (e.g. BCG vaccine) should not be given to infants less than 12 months after birth following in utero infliximab exposure, and that administration […]

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Case report of bosentan and sildenafil use in lactation and medication disposition in breastmilk.

ENTIS affiliated researchers from the Department of Pharmaceutical and Pharmacological Sciences, KU Leuven have published a case report of bosentan and sildenafil use in lactation. This report, from the IMI ConcePTION project, presents the clinical and pharmacokinetic data of a single mother-infant pair exposed to bosentan and sildenafil for the treatment of pulmonary arterial hypertension (PAH) during lactation. More information […]

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