Researchers from the EUROmediCAT network have published a case-malformed disproportionality analysis to identify medication-anomaly signals using a novel signal detection method. More information is available here. Photo by Aleksandre Lomadze on PEXELS
» Read more
Researchers from the University of Hong Kong, China, have published a study investigating the risk of ASD or ADHD following acetaminophen (paracetamol) use in pregnancy using a sibling-controlled design. More information is available here.
» Read more
Researchers from the ConcePTION project have published a cross-sectional observational study of primary data collected via primary caregiver questionnaire describing the long term health complaints of individuals exposed and unexposed to VPA in utero. An open access link to the research is provided by the authors. Photo by Ian Taylor (check our Ian’s website for more fantastic photos)
» Read more
Researchers from the United States have published a large target trial emulation study including data from eight health systems across eight states, investigating the risk of adverse neonatal and obstetric outcome following RSV vaccination in pregnancy. The study provides largely reassuring safety evidence particularly for obstetric/neonatal outcome, whilst also identifying a possible small increased risk of maternal hypertensive disorders of […]
» Read more
Researchers from Teva Pharmaceutical Industries Limited have utilised French national health data to investigate risks of major malformation and other adverse pregnancy outcomes following prenatal modafinil exposure. More information available here. Photo by Anna Shvets from PEXELS.
» Read more
Researchers from The University of Melbourne (Australia) have published an analysis of data collected in the Raoul Wallenberg Australian Pregnancy Register of Antiepileptic Drugs. The study investigates whether in utero exposure to specific types of ASM monotherapies is associated with poorer neurocognitive outcomes compared with ASM-unexposed children. More information is available here. Photo by Anna Shvets on Pexels.
» Read more
Researchers from the Rollins School of Public Health at Emory University (Atlanta, GA, USA) have published an update of the global status of spina bifida and anencephaly prevention by folic acid. More information is available here. Photo by Beelith USA
» Read more
An international collaboration of researchers have published a systematic review and meta-analysis comparing the safety of anti-TNF blockers, vedolizumab and ustekinumab in pregnancy. Although higher risks were observed for vedolizumab and ustekinumab in comparison with anti-TNF inhibitors, the authors concluded that this was likely related to longer disease duration, prior biologic exposure, and more active disease, More information is available […]
» Read more
Researchers from the Department of Epidemiology, Biostatistics, and Community Health Sciences, at the Ben-Gurion University of the Negev (Beer-Sheva, Israel) have published a large analysis of data collected from the Southern Israeli Pregnancy Registry project. More information is available here,
» Read more
Researchers from Harvard T.H. Chan School of Public Health and Mass General Brigham for Children (Boston, USA) have published an updated analysis of data from the North American AED Pregnancy Registry. The study assesses the risk of major malformation among infants of women using common ASM polytherapies during the first trimester. More information is available here. Photo by Polina Tankilevitch […]
» Read more