Category: News

Oropouche virus (OROV) is an arbovirus endemic in Latin America and the Caribbean. A recent outbreak of the virus has been associated with reports of pregnant women infected with OROV who have had miscarriages and stillborn fetuses with placental, umbilical blood and fetal somatic organ samples that were RT-PCR positive for OROV and negative for other arboviruses. Travelers with Oropouche […]

ENTIS members from the University of Oslo have developed a novel algorithm to more completely detect and date early pregnancy outcomes (i.e., miscarriages, elective terminations, ectopic pregnancies, molar pregnancies, stillbirths, and live births) using diagnostic codes from primary and secondary care registries to complement information from the national birth registry. More information can be found here. Photo by Luke Chesser […]

The Pan American Health Organizartion (PAHO) has issued an epidemiological alert describing possible cases of vertical Oropouche virus transmission (from mother to fetus) in Brazil. The alert describes two recent cases of suspected vertical transmission in pregnancy, one of which ended in intrauterine fetal death, the second in early pregnancy miscarriage. The alert also describes a small number of historical […]

Data collected from Dutch and Danish clinical records has been used to investigate the safety of allopurinol use in pregnancy. The authors also conducted a systematic review. More information is available here.

Pregnancy safety data for golimumab have been published using global pharmacovigilance data collected by Janssen Pharmaceuticals. The authors of the publication concluded that rates of adverse pregnancy outcomes and major congenital anomalies in prospectively reported pregnancy cases were consistent with published background rates for the general population. More information can be found here.

Researchers from the Pregnancy and Drug Information Center in Tokyo have published a comparative cohort study comparing fetal malformation outcomes between those exposed to (i) fluoroquinolones (fluoroquinolone group), (ii) β-lactams (infectious control group), or (iii) other agents considered to be nonteratogenic in humans (nonteratogenic control group) during the first trimester. The incidence of major congenital anomalies was not found to […]