Pregnancy outcomes after exposure to interferon beta

An international collaboration of researchers led from StatFinn & EPID Research in Mölndal, Sweden and Espoo, Finland have published a comparative cohort study using linked national healthcare register data from Sweden and Finland. The study investigated the risk of adverse pregnancy outcomes following maternal perinatal exposure to interferon beta in the treatment of multiple sclerosis. More information can be found […]

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Risk of neurodevelopmental impairment following exposure to antiepileptic drugs in pregnancy

A collaborative of French researchers have conducted a nationwide cohort study investigating the risk of neurodevelopmental disorders among infants of women who used antiepileptic drugs during pregnancy. The study, which included >1.7 m children, identified strong associations between valproate use in pregnancy and neurodevelopmental disorder, while pregabalin use in pregnancy was associated with a marginal increased risk. More information can be […]

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Exploring the impact of methodological bias and data confounding in pregnancy pharmacovigilance

Professor Gideon Koren and Professor Asher Ornoy from the Adelson Faculty of Medicine, Ariel University, Israel have published a review exploring the impact of methodological bias and data confounding in pregnancy pharmacovigilance, using the specific example of the SSRI exposure in pregnancy data. More information can be found here. Photo by Ben Blennerhassett on Unsplash

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Motherisk Journal Article: How much folic acid is sufficient in women using antiepileptic drugs during pregnancy?

Professor Yusuf Kaplan, formerly of the Izmir TIS, and Professor Gideon Koren from the Adelson Faculty of Medicine, Ariel University, Israel and the Motherisk Israel Program have published a review article discussing the available evidence regarding the folic acid requirements for women who use antiepileptic drugs in pregnancy. More information can be found here. Photo by Iñigo De la Maza on Unsplash

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Small increased risk of birth defects following first trimester hydroxychloroquine use

A collaborative of researchers from Harvard University’s Medical School and School of Public Health have published a propensity score matched analysis of US Medicaid data which has identified a small increased risk of overall malformation following first trimester hydroxychloroquine use in the treatment of rheumatic conditions. The small increased risk predicted by this study suggest that an additional case of malformation could […]

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