Large population-based study of duloxetine use in pregnancy published

Researchers from the University of Copenhagen and Copenhagen University Hospital have published a large population-based observational study investigating the safety of gestational duloxetine use. The study was conducted using data from registers in Sweden and Denmark, and provided reassuring results regarding major congenital malformation and stillbirth risks. More information can be found here.

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SARS-CoV-2 infection and stillbirth aetiology

An interesting case report has described syncytiotrophoblasts as a major cellular target for SARS-CoV-2 infection of the placenta, and suggested that the possible stillbirth risks of placentotropic SARS-CoV-2 may be related to hampered maternal and/or fetal perfusion of the placenta. More information can be found here. Photo by João Paulo de Souza Oliveira on Unsplash

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Details published of the prospective and multi-centre China Teratology Birth Cohort

Researchers affiliated to the National Center for Birth Defect Monitoring of China have published a protocol describing a new multi-centre teratogen surveillance network in China. The surveillance system will combine pregnancy health records from numerous hospital sites to collect data on gestational medication use and pregnancy outcomes. More information can be found here. Photo by Samuel Scalzo on Unsplash

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Tocilizumab use for the treatment of COVID-19 in pregnancy

Researchers from Mount Sinai Hospital, Toronto, Canada have published a narrative review of tocilizumab use for the treatment of COVID-19 in pregnancy. They located data describing 610 tocilizumab-exposed pregnancies, with 20 receiving treatment due to severe COVID-19. This review may be helpful for those providing counselling on the safety of COVID-19 treatments in pregnancy. More information can be found here. […]

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