Large, population-based cohort study finds no evidence that seasonal influenza vaccine is associated with major malformation

Researchers from the London School of Hygiene and Tropical Medicine and Queen Mary University of London have analysed pseudonymised UK primary care data from the Clinical Practice Research Datalink to investigate malformation risks following seasonal influenza vaccination exposure in pregnancy. They found no evidence for an increased risk following exposure at any stage of pregnancy or in the first trimester […]

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Narrative review published summarising the impact of coronaviruses on pregnant women

Researchers from Lausanne University Hospital and the Swiss Institute of Primary Health Care have published a narrative review which summarises the existing knowledge about how coronaviruses (including MERS, SARS and SARS-CoV-2) can impact pregnant patients. The review also includes a useful discussion of the therapeutic treatment options available for pregnant women, and contrasts existing antenatal management guidance proposed by RCOG, […]

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Study investigating neurodevelopment outcomes following caffeine consumption in pregnancy

Researchers from the University of Gothenburg and the Norwegian Institute of Public Health have published a study conducted using data from the Norwegian Mother, Father and Child Cohort Study, which has investigated the impact of maternal caffeine consumption during pregnancy on offspring neurodevelopment. More information can be found here. Photo by Mike Kenneally on Unsplash

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Oral fluconazole associated with a small increase in the risk of musculoskeletal malformation

A collaborative of researchers from Harvard Medical School, Brigham and Women’s Hospital Boston and Harvard T H Chan School of Public Health have analysed data from the Medicaid Analytic eXtract and found a small increase in the risk of musculoskeletal malformation following first trimester oral fluconazole use. More information cab be found here. Photo by kgrkz on Unsplash

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Pregnancy outcomes in patients treated with leflunomide

A collaborative of researchers from the Swedish Neuroscience Institute and Sanofi have published an updated report of pregnancies which occurred in patients undergoing leflunomide treatment in clinical trials or collected by the manufacturer in routine post-marketing surveillance. More information can be found here. Photo by Hal Gatewood on Unsplash

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Scorpion envenomation in pregnancy

Researchers from the Ahvaz Jundishapur University of Medical Sciences in Iran have published a small case series of obstetric and fetal outcomes following scorpion envenomation during pregnancy. More information can be found here. Photo by Wolfgang Hasselmann on Unsplash

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