No link between triptan use in pregnancy and ADHD in the offspring

ENTIS affiliated researchers from the Pharmacoepidemiology and Drug Safety Research Group, , PharmaTox Research Initiative at the University of Oslo have published a study investigating whether an association exists between maternal use of triptans during pregnancy and diagnosis or symptoms of attention-deficit hyperactivity disorder among their offspring. More information can be found here. Photo by Anthony Tran on Unsplash

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Topiramate use in pregnancy associated with increased risks of autism spectrum disorder and intellectual disability in the offspring

JAMA Neurology have recently published a population-based cohort study which used health and social register data from Denmark, Finland, Iceland, Norway, and Sweden to investigate neurodevelopmental outcomes of children (up to age 8) exposed to antiseizure medications in pregnancy. Increased risks of autism spectrum disorder and intellectual disability were observed for children exposed to topiramate in utero. More information can […]

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Prenatal antiseizure medication exposure and neurodevelopmental outcomes

An international collaboration of researchers led from Haukeland University Hospital in Norway have published a population-based cohort study using health register and social register data from Denmark, Finland, Iceland, Norway, and Sweden investigating whether children exposed prenatally to antiseizure medications have increased risk of neurodevelopmental disorders. More information is available here.

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Systematic review and meta-analysis of protease inhibitor-based antiretroviral therapy in pregnancy

Researchers from the National Perinatal Epidemiology Unit at the University of Oxford have published a systematic review and meta-analysis investigating the risk of preterm birth, impaired fetal growth, stillbirth and neonatal death following protease inhibitor-based antiretroviral therapy use in pregnancy. More information can be found here. Photo by Mika Baumeister on Unsplash

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Large study provides further reassurance about topical corticosteroid use in pregnancy.

Researchers from the Department of Clinical Pharmacology at Copenhagen University Hospital have published a large population-based propensity score matched comparative cohort study which found no association between topical corticosteroid use in pregnancy and an increased risk of SGA or low birth weight. Their results also suggested that moderate to large increased risks were unlikely, even with use of large amounts of […]

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