Sibling controlled cohort study finds no evidence for an increased risk of autism, ADHD or intellectual disability following paracetamol (acetaminophen) use in pregnancy

Researchers from the Karolinska Institutet in Stockholm, Sweden, have published a population-based cohort study examining the risks of autism, ADHD or intellectual disability following paracetamol (acetaminophen) use in pregnancy. No increased risks were identified in sibling control analyses, suggesting that associations observed in other models (i.e. non-sibling controlled) may have been attributable to confounding. More information is available here.

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Study finds no increased risk of autism spectrum disorder with maternal topiramate use in pregnancy

A large population-based cohort study using data from US healthcare utilisation databases (Medicaid and MarketScan) suggests that topiramate use in pregnancy may not be associated with an increased risk of autism. More information is available here, This finding contrasts with a 2022 study which suggested an almost 3-fold increased risk following in utero topiramate exposure. A helpful overview of these […]

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