A systematic safety surveillance approach assessing congenital malformation risk following prenatal antipsychotic exposure

Researchers from the Division of Pharmacoepidemiology and Pharmacoeconomics at the Brigham and Women’s Hospital in Boston, USA, have published a study utilising a tree-based scan statistic (TBSS) approach evaluating the risk of a range of specific malformations and malformation groupings and their association with prenatal antipsychotic exposure. More information is available here. Photo by Pankaj Patel on Unsplash

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Target trial emulation studying the timing of high-dose folic acid supplementation among women taking antiseizure medications and malformation risk

A collaboration of researchers from Denmark, Iceland, Norway, and Sweden have published a target trial emulation study assessing the risk of malformation associated with the timing of high-dose folic acid supplementation among women taking antiseizure medications. More information is available here. Photo by Ocean Ng on Unsplash

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Living systematic review of Mpox vaccination in pregnancy

Researchers from the Argentine Cochrane Center have published a living systematic review and meta-analysis investigating the safety and effectiveness of Mpox vaccine in pregnancy and childhood. This initial evidence synthesis described no increased risk of miscarriage, stillbirth or preterm delivery, but a statistical association was observed with malformation risk. More information can be found here. Photo by National Institute of […]

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Study examines maternal and fetal outcomes following statin discontinuation in pregnancy

Researchers from the Sungkyunkwan University Suwon/Seoul in South Korea have published an analysis of the National Health Insurance Database of South Korea evaluating the risks of maternal cardiovascular, gestational, and fetal outcomes associated with continuing versus discontinuing statin therapy before the last menstrual period. More information is available here. Photo by Daniel Dan on Unsplash

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