Category: News

A collaborative of researchers from Nordic countries and the US have published a population-based comparative cohort study including approximately 2.4 million pregnancies ending in live births in Denmark, Iceland, Norway, and Sweden (2003-2017) and approximately 1.8 million in the US, investigating the risk of major malformation following maternal first trimester atomoxetine use. More information can be found here. Photo by […]

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Researchers affiliated to the PharmacoEpidemiology and Drug Safety Research Group at the University of Oslo, led by ENTIS member Professor Hedvig Nordeng, have published a large comparative cohort study investigating childhood ADHD risks following maternal benzodiazepine/z-drug hypnotic use in pregnancy. The full study sample consisted of more than 82,000 singleton pregnancies, with 681 offspring exposed to benzodiazepines or z-drug hypnotics […]

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A collaboration of researchers from the US and Nordic countries have published a very large population-based cohort study including more than 6.5 million pregnancies. The study investigated malformation risks following antipsychotic use and generally provides some very reassuring data. More information can be found here. Photo by Christina Victoria Craft on Unsplash

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US researchers have published a study investigating both maternal and fetal outcomes among women using buprenorphine or methadone for opioid use disorder in pregnancy. The results indicate a lower risk of adverse neonatal outcomes for buprenorphine exposed pregnancies while the risk of adverse maternal outcomes was similar among those using buprenorphine and methadone. More information can be found here. Photo […]

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A collaboration of ENTIS affiliated researchers led by Dr Kim Dao and Dr Ursula Winterfeld from Swiss Teratogen Information Service and Clinical Pharmacology Service, have published a comparative cohort study of the reproductive safety of trazadone use in early pregnancy. More information can be found here. Photo by Gregory Pappas on Unsplash

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ENTIS affiliated researchers from the UK, Denmark and Israel have published a literature review and critical appraisal which explores whether recent SmPC updates applied to some pregabalin products are justified, and provides clarity on the risk-benefit balance for pregabalin use in early pregnancy. This publication was developed after the ENTIS Board and Scientific Committee submitted an official communication to the EMA […]

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Researchers from the EUROlinkCAT project have published the results of a survey investigating parental satisfaction with information received about their child’s congenital anomaly. More details can be found here. Photo by sofatutor on Unsplash

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Researchers from the University of California, San Diego, Mother-to-Baby research programme have published a study indicating that NSAID use in the first trimester may be associated with an increased risk of small for gestational age. More information can be found here. Photo by Patricia Prudente on Unsplash

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A collaborative of researchers from Radboud University Medical Center, the Netherlands Pharmacovigilance Centre Lareb and Maastricht University, led by ENTIS associate member Dr Marleen van Gelder, have published a prospective comparative cohort study investigating preeclampsia risk among women exposed to calcium-based antacids and PPIs during pregnancy. More information can be found here. Photo by Mufid Majnun on Unsplash

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