Risk of neurodevelopmental impairment following exposure to antiepileptic drugs in pregnancy

A collaborative of French researchers have conducted a nationwide cohort study investigating the risk of neurodevelopmental disorders among infants of women who used antiepileptic drugs during pregnancy. The study, which included >1.7 m children, identified strong associations between valproate use in pregnancy and neurodevelopmental disorder, while pregabalin use in pregnancy was associated with a marginal increased risk. More information can be […]

» Read more

3rd International Joint Meeting of OTIS/ENTIS 2018 Call for Abstracts

Abstract submissions are now open for the 3rd International Joint Meeting of ENTIS and OTIS to be held in Newcastle upon Tyne, UK from September 6th to 8th, 2018 at the Newcastle University.  The deadline for submissions is Sunday, April 15th. Abstracts for the ENTIS-OTIS meeting should be submitted using the online submission form that can be found here. Submitting authors will be notified by […]

» Read more

ACE inhibitors in pregnancy: Recent study from the U.S. suggests no increase in risk of major malformations with exposure during the first trimester among women with hypertension

In January 2017 Obstetrics & Gynecology published an article on Angiotensin-Converting Enzyme Inhibitors and the Risk of Congenital Malformations“ by Brian T Bateman et al. As data on the teratogenic potential of ACE inhibitor (ACEI) are partly conflicting, this pharmacoepidemiologic study wanted to analyze the association between first trimester ACEI exposure and the risk of overall major malformations, of cardiovascular […]

» Read more