ACE inhibitors in pregnancy: Recent study from the U.S. suggests no increase in risk of major malformations with exposure during the first trimester among women with hypertension

In January 2017 Obstetrics & Gynecology published an article on Angiotensin-Converting Enzyme Inhibitors and the Risk of Congenital Malformations“ by Brian T Bateman et al. As data on the teratogenic potential of ACE inhibitor (ACEI) are partly conflicting, this pharmacoepidemiologic study wanted to analyze the association between first trimester ACEI exposure and the risk of overall major malformations, of cardiovascular […]

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