Birth defect risks following maternal antihypertensive use

US National Birth Defects Study data has been analysed to investigate malformation risks following maternal antihypertensive medication use in pregnancy. Although the authors report some statistically significant associations with specific anomalies, these findings were not related to any particular class of medications. Furthermore, associations were seemingly based on small numbers of exposed and affected infants, and the impact of the underlying maternal condition could not be accounted for in the analysis. Full details of the study have been published in Birth Defects Research.


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