Prenatal exposure to benzodiazepine and z-hypnotics and fifth-grade scholastic skills
A collaboration between researchers from the PharmacoEpidemiology and Drug Safety Research Group at the University of Oslo and the Department of Epidemiology at the University of North Carolina Chapel Hill has provided a study emulating target trials using data from the Norwegian Mother, Father and Child Cohort Study. The trials investigate the effects of initiating benzodiazepine or z-hypnotic treatment in early, mid and late pregnancy on fifth-grade numeracy and literacy scholastic skills in children. Although some of the analyses suffered from limited statistical power, the authors concluded that the findings provide reassurance for patients in need of benzodiazepines and z-hypnotics during pregnancy. More information can be found here.