Study of male genital anomalies following maternal oral contraceptive use in pregnancy

A collaboration of researchers from Aarhus University and the University of Copenhagen have performed an analysis of the Danish National Birth Cohort to investigate the risk of cryptorchidism (undescended testicles) and hypospadias (abnormal positioning of the urethral opening) following the maternal use of oral contraceptives. More information can be found here. Image by mmmCCC from Pixabay

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Literature review: Risk of adverse fetal effects following short-term second trimester NSAID use

Researchers from Embryotox, the Berlin TIS, have recently published the results of their systematic review focussing on the risk of prenatal ductus arteriosus constriction, oligohydramnios, neonatal renal failure and primary pulmonary hypertension following maternal short-term use of NSAIDs in the second trimester of pregnancy. More information can be found here.

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Interesting academic highlights article discussing the FDAs pregnancy and lactation labelling rule

Pregnancy labelling of medications is a hotly debated issue in the field of teratology, and several studies have shown the limitations of providing pregnancy safety category ratings for medicines. In this recent academic highlights article, the authors summarise discussions which were held at an April 2017 meeting focussed on pregnancy pharmacogivilance and the FDAs pregnancy and lactation labelling rule. Further […]

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