On the 18th September 2019, ENTIS issued an official response to the European Medicines Agency (EMA) Pharmacovigilance Risk Assessement Committee (PRAC) concerning the recommendations which were made about ondansetron use by pregnant women, as detailed in the minutes of their meeting held from the 8th to 11th July. The official ENTIS response statement can be read here.
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A collaboration of researchers from the Centers for Disease Control and Prevention’s National Center on Birth Defects and Developmental Disabilities, the University of Texas, Emory Univeristy and the University of Utah have published an analysis of data collected by the National Birth Defects Prevention Study (1997-2011) to describe the defects most commonly observed among the infants of women with pregestational […]
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Researchers from Aalborg University in Denmark have undertaken an analysis of data from the Danish National Birth Cohort and North Denmark Region Pregnancy Cohort to assess the risk of birth defects following maternal antithyroid drug use. Further infromation can be found here. Photo by kgrkz on Unsplash
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The EURAP study group have undertaken a Cochrane-Armitage linear trend analysis of their prospective data was to assess how changes in AED treatment since 2000-2005 has altered the prevalence of major congenital malformations in their dataset. More information can be found here. Photo by Brett Jordan on Unsplash
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Researchers from the University of California San Diego have performed an analysis of data collected by the Organization of Teratology Information Specialists to investigate birth defect, preterm delivery, and small for gestational age risks following maternal oseltamivir use in pregnancy. More information can be found here. Photo by Kelly Sikkema on Unsplash
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The European Referece Network for Congenital Malformations and Intellectual Disability have conducted a review of published and unpublished evidence relating to the diagnosis and management of fetal valproate spectrum disorder, and subsequently issued management recommendations based on the evidence from their review in combination with expert and patient opinion. More information can be found here. Photo by Samuel Zeller on […]
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A collaboration of researchers from Aarhus University and the University of Copenhagen have performed an analysis of the Danish National Birth Cohort to investigate the risk of cryptorchidism (undescended testicles) and hypospadias (abnormal positioning of the urethral opening) following the maternal use of oral contraceptives. More information can be found here. Image by mmmCCC from Pixabay
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Researchers from Embryotox, the Berlin TIS, have published their data concerning maternal fosfomycin use in pregnancy. More information can be found here. Photo by Cassidy Rowell on Unsplash
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Associate ENTIS member Dr Michael Ceulemans and collegues from KU Leuven in Belgium have published a retrospective analysis of the pregnancy and lactation related enquiries made to the national poison centre between January 2012 and December 2017. More information can be found here. Photo by Berkeley Communications on Unsplash
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Researchers from Embryotox, the Berlin TIS, have recently published the results of their systematic review focussing on the risk of prenatal ductus arteriosus constriction, oligohydramnios, neonatal renal failure and primary pulmonary hypertension following maternal short-term use of NSAIDs in the second trimester of pregnancy. More information can be found here.
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