Maternal and perinatal outcomes following pre-Delta, Delta, and Omicron SARS-CoV-2 variants infection among unvaccinated pregnant women

Researchers affiliated with the French and Swiss Covi-Preg registry, led by ENTIS members from the Swiss Teratology Information Service, have published a prospective cohort study describing the maternal and perinatal outcomes among unvaccinated pregnant women that tested positive for SARS-CoV-2 during the pre-Delta, Delta, and Omicron periods. More information can be found here.

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Medication Use among Pregnant and Breastfeeding Women during the COVID-19 Pandemic

ENTIS research led by Dr Michael Ceulemans (Lareb TIS, Netherlands) and Prof Hedvig Nordeng (Pharmacoepidemiology and Drug Safety Research Group, University of Oslo) has been published describing the prevalence of medication use in pregnancy and breastfeeding during the first wave of the COVID-19 pandemic. The research highlighted that perinatal medication use was highly prevalent during the first wave, underlining the […]

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Tocilizumab use for the treatment of COVID-19 in pregnancy

Researchers from Mount Sinai Hospital, Toronto, Canada have published a narrative review of tocilizumab use for the treatment of COVID-19 in pregnancy. They located data describing 610 tocilizumab-exposed pregnancies, with 20 receiving treatment due to severe COVID-19. This review may be helpful for those providing counselling on the safety of COVID-19 treatments in pregnancy. More information can be found here. […]

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COVID-19 vaccine in pregnancy; Preliminary miscarriage data published

Researchers from the US CDC’s v-safe registry have published some preliminary data regarding the risk of miscarriage. Among women who were vaccinated either prior to pregnancy, or before 20 weeks gestational age, the age standardised cumulative risk of miscarriage was estimated to be 12.8% (95% CI: 10.8–14.8%), and in keeping with the expected background risk. More details can be found […]

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