ENTIS-OTIS 2024 conference website launched
The organisers of the 2024 ENTIS-OTIS conference, being held in Nyborg, Denmark (September 12-15th, 2024), have launched the conference website.
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Study finds no increased risk of autism spectrum disorder with maternal topiramate use in pregnancy
A large population-based cohort study using data from US healthcare utilisation databases (Medicaid and MarketScan) suggests that topiramate use in pregnancy may not be associated with an increased risk of autism. More information is available here, This finding contrasts with a 2022 study which suggested an almost 3-fold increased risk following in utero topiramate exposure. A helpful overview of these […]
» Read moreMedication use in pregnancy on the rise
Researchers from Aarhus University (Denmark) have published an analysis of population-level prescribing data which provides evidence of the rising prevalence of medication use in pregnancy. More information is available here.
» Read moreLive births following leflunomide exposure and malformation risks
Researchers from the University of Bremen have published data from the German Pharmacoepidemiological Research Database describing the outcomes of 205 pregnancies where leflunomide dispensing overlapped the first 8 weeks of pregnancy. More information is available here. Photo by Amanda Jones on Unsplash
» Read moreAn updated systematic review and meta-analysis of neonatal outcomes among pregnant women with asthma
An international group of researchers have published an updated systematic review and meta-analysis (original published in 2013) investigating the risk of adverse neonatal outcomes among pregnant women with asthma. More information is available here. Photo by Sincerely Media on Unsplash
» Read moreBELpREG; a real-world data source on medication use in pregnancy in Belgium
ENTIS affiliated researchers based at KU Leuven in Belgium have published a description of their BELpREG registry. More information is available here. Photo by Christina @ wocintechchat.com on Unsplash
» Read moreJoint ENTIS-OTIS Meeting 2024 (Nyborg, Denmark): Call for abstracts
Prospective delegates are invited to submit research abstracts for the Joint ENTIS-OTIS Meeting which will be held in Nyborg, Denmark from the 12th to 15th September. The abstract submission deadline is 28th March 2024, and authors will be notified of acceptance by 26th April 2024. Please see here for the abstract submission template and instructions for authors. More information about […]
» Read moreSystematic review of pregnancy safety data for small molecules used in the treatment of inflammatory bowel disease
Clinicians and researchers from the Leeds Gastroenterology Institute (UK) have published a systematic review which has identified preliminary safety data for tofacitinib, filgotinib, upadacitininb, and ozanimod, small molecules used in the treatment of inflammatory bowel disease. More information is available here.
» Read moreStudy of 379 pregnancies exposed to dimethyl fumarate
The final analysis of an international pregnancy registry of women with multiple sclerosis treated with dimethyl fumarate has recently been published. The findings demonstrated no adverse effect of dimethyl fumarate exposure on birth defect, preterm birth, and spontaneous abortion risks. More information is available here.
» Read moreImpact of maternal first trimester valproate treatment regimen on the risk of birth defects
Researchers from TIS Berlin (Embryotox Center of Clinical Teratology and Drug Safety in Pregnancy, Charité – Universitätsmedizin Berlin) have published an analysis of 484 first trimester valproate exposed pregnancies which investigates the effects of valproate dose and first trimester treatment discontinuation on the risks of spontaneous abortion and major birth defects. More information is available here.
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