Category: News

Researchers from the Lombardy region, Italy, have published a propensity score stratified comparative cohort study of antihypertensive medication use in pregnancy. Additional details can be found here.

Researchers from the Department of Clinical Pharmacology at Copenhagen University Hospital have published a large population-based propensity score matched comparative cohort study which found no association between topical corticosteroid use in pregnancy and an increased risk of SGA or low birth weight. Their results also suggested that moderate to large increased risks were unlikely, even with use of large amounts of […]

A study published in the Annals of Internal Medicine has suggested that there may be an association between paternal preconception exposure to antidiabetic medication and increased birth defect risks. Of note, the findings suggested clinically relevant increased risks among those exposed to metformin. However, the potential for confounding by indication may also have been highlighted. More information available here. Photo […]

Researchers based in Denmark have conducted a national population-based comparative cohort study which included between 895 and 1,900 mirtazapine exposed pregnancies (outcome dependent). The results indicated that mirtazapine exposure in pregnancy is not associated with increased risks of major congenital malformation, miscarriage, stillbirth or neonatal death. More details can be found here. Photo by Ben Blennerhassett on Unsplash

Researchers from Teva Pharmaceuticals have published a large case series of 647 glatiramer acetate exposed pregnancies that were reported to the global pharmacovigilance database. More information can be found here. Clinical researchers affiliated to two neurology departments in Western Australia have published a small case series of 14 pregnancies in 12 MS patients who had been exposed to ocrelizumab within […]

A collaborative of researchers affiliated to Copenhagen University Hospitals have published a large population-based study of more than 7,000 tramadol exposed pregnancies, finding no evidence for increased risks of miscarriage or major malformation. More information can be found here. Photo by Christina Victoria Craft on Unsplash

Researchers from Addis Ababa University have published a systematic review and meta-analysis of 24 studies which provided efficacy or safety data for artemisinin-based combination therapy (ACT) for uncomplicated malaria in pregnancy. More information can be found here.

Writing in the journal Obstetric Medicine, ENTIS members Prof Per Damkier (Odense University Hospital/University of Southern Denmark) and Dr Kenneth Hodson (UKTIS) provide a succinct critical appraisal of the paracetamol in pregnancy safety data. The editorial is openly available here. Photo by James Yarema on Unsplash

A collaboration of researchers from Lausanne University Hospital, and the Universities of Lausanne, Basel and Bern have published data from the Swiss Helsana claims dataset (2014-2018). The researchers described the medications most commonly utilised in the treatment of chronic medical conditions in Switzerland. More information can be found here. Photo by Campaign Creators on Unsplash