Category: News

The Italian Societies of Toxicology, Neuropsychopharmacology, Psychiatry, Obstetrics and Gynecology, Drug Addiction, and Addiction Pathology have published joint consensus recommendations regarding the management of depressive disorders in pregnancy. These recommendations focussed on five key areas including: (i) the importance of management of anxiety and depressive disorders in pregnancy; (ii) the overall risk of malformation with antidepressant and anxiolytic drugs; (iii) […]

Researchers affiliated to the Poison Control Center and Teratology Information Center in Bergamo, Italy, have published a case series of regnancy and fetal outcomes following maternal use of long-acting injectable antipsychotics. More information is available here. Photo by Mufid Majnun on Unsplash

Researchers from Teva Pharmaceuticals and St. Josef-Hospital (Bochum, Germany) have published the pregnancy and fetal outcomes for a cohort of 618 women who used glatiramer acetate in all three trimesters of pregnancy. More information can be found here.

Utilising data from the Colorado-based Children’s Hospital Immunodeficiency Program (CHIP), a team of researchers have published a retrospective comparative cohort study of pregnancy and fetal outcomes following first trimester integrase inhibitor use (dolutegravir, elvitegravir or raltegravir). The study describes increased risks of congenital anomalies among the first trimester integrase inhibitor exposed in comparison with those born to women with HIV […]

Experts from 13 countries and professionally diverse backgrounds took part in the development of a series of recommendations focusing on the importance of including the study of infant neurodevelopment as a core feature of pregnancy drug safety studies. These recommendations outline the core neurodevelopmental outcomes, optimization of methodological approaches and barriers to conducting pregnancy drug safety studies including neurodevelopmental outcomes. […]

Researchers from Lyon, France have published an updated systematic review and meta-analysis of malformation risk following maternal first trimester proton pump inhibitor exposure. More information can be found here.

Researchers from Qilu Medical University, China, have published a comparative analysis of the safety of propylthiouracil and methimazole in the treatment of hyperthyroidism in pregnancy. More information can be found here. Photo by SHAMBHAVI SINGH on Unsplash

Researchers and ENTIS affiliates from KU Leuven, Belgium, have published details of their newly developed BELpREG data registration system which enables comprehensive “real-world” data collection on perinatal medication use and mother-infant outcomes via online questionnaires. More information about the development and design of the system available here.