Category: News

Researchers from the Innovative Medicines Initiative (IMI) ConcePTION project have published a set of recommendations about the core data elements which should be collected when performing studies of medication use in pregnancy. These recommendations include all the key variables that are required in studies assessing both immediate pregnancy/infant outcomes, and longer-term childhood outcomes following maternal medication use in pregnancy. Each […]

Researchers with access to the VigiBase database of adverse drug reactions have conducted a disproportionality analysis of adverse pregnancy outcomes to identify safety signals associated with ganciclovir or valganciclovir use in pregnancy. More information can be found here. The authors of the study have also provided ENTIS with a visual abstract of their study: Photo by Wengang Zhai on Unsplash

Researchers from the Sapienza University Working Group on Cystic Fibrosis in Pregnancy have published a case report on the outcome of pregnancy in a woman treated with elexacaftor, tezacaftor, ivacaftor combination during the second and third trimester of pregnancy (following discontinuation in the first trimester). More information available here. Photo by Mockup Graphics on Unsplash

Researchers affiliated to the National Health Research Institutes in Taiwan have published a large population-based cohort study investigating the risk of ADHD, ASD or Tourette Syndrome following maternal leukotriene-receptor antagonists use in pregnancy. Further information is available here. Photo by Robina Weermeijer on Unsplash

Researchers from the Eunice Kennedy Shriver National Institute of Child Health and Human Development-Obstetrics Fetal Pharmacology Research Centers Network have conducted a long-term follow-up study to determine the impact pravastatin treatment in pregnant women at high risk of preeclampsia may have on child health, growth, and neurodevelopment. The results of this small study, although limited by the trial’s sample size […]

Communication experts from the IMI ConcePTION project have produced a toolkit will allow organisations with limited resources to design communication campaigns to stimulate reporting of medicine use during pregnancy and breastfeeding to appropriate organisations. ENTIS members are invited to join the online launch of this toolkit on 15th March, 1500-1600 Central European Time (CET). For more information about the toolkit, […]

Researchers affiliated to the Harvard T.H. Chan School of Public Health have published an analysis of data from the US-based pediatric HIV/AIDS cohort study investigating the risk of neurodevelopmental problems in HIV-exposed uninfected 5-year-old children exposed to ART medication in utero. More information can be found here. Photo by CDC on Unsplash

FactCheck.org have published an article on the interpretation of the available evidence surrounding autism and ADHD risks in children exposed to acetaminophen (paracetamol) in utero. The article concludes that there is currently no strong evidence that acetaminophen use during pregnancy causes autism or ADHD in children, and that experts continue to recommend use of the drug during pregnancy when necessary […]

Researchers affiliated with the Hamad Medical Corporation in Doha (Qatar) have published a small case series examining the impact of tyrosine kinase inhibitors on fatherhood in patients with chronic myeloid leukemia (CML). More information can be found here. Photo by Derek Thomson on Unsplash

Researchers, including several ENTIS members and Swiss Teratology Information Service colleagues, have published a systematic review and meta-analysis of major congenital malformation risk after first-trimester exposure to metformin in women with PCOS and pre-gestational diabetes mellitus. More information can be found here. Photo by Mae Mu on Unsplash