ConcePTION Project: Communication toolkit launch – 15th March

Communication experts from the IMI ConcePTION project have produced a toolkit will allow organisations with limited resources to design communication campaigns to stimulate reporting of medicine use during pregnancy and breastfeeding to appropriate organisations. ENTIS members are invited to join the online launch of this toolkit on 15th March, 1500-1600 Central European Time (CET). For more information about the toolkit, […]

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Limited evidence of a link between acetaminophen (paracetamol) and autism or ADHD

FactCheck.org have published an article on the interpretation of the available evidence surrounding autism and ADHD risks in children exposed to acetaminophen (paracetamol) in utero. The article concludes that there is currently no strong evidence that acetaminophen use during pregnancy causes autism or ADHD in children, and that experts continue to recommend use of the drug during pregnancy when necessary […]

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Systematic review and meta-analysis of malformation risk following maternal metformin use in pregnancy

Researchers, including several ENTIS members and Swiss Teratology Information Service colleagues, have published a systematic review and meta-analysis of major congenital malformation risk after first-trimester exposure to metformin in women with PCOS and pre-gestational diabetes mellitus. More information can be found here. Photo by Mae Mu on Unsplash

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Study provides data on childhood infection risk following in utero anti-TNFα monoclonal antibody exposure

A collaboration of researchers from Shanghai Jiao Tong University, Fudan University and Aarhus University have published a population-based cohort study investigating infectious disease in the offspring of women with inflammatory bowel disease in pregnancy. The study also investigated infection risk among those with in utero exposed to anti-TNFα monoclonal antibody. More information can be found here.

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Large population-based study suggests no increased major malformation risk following maternal first trimester atomoxetine use

A collaborative of researchers from Nordic countries and the US have published a population-based comparative cohort study including approximately 2.4 million pregnancies ending in live births in Denmark, Iceland, Norway, and Sweden (2003-2017) and approximately 1.8 million in the US, investigating the risk of major malformation following maternal first trimester atomoxetine use. More information can be found here. Photo by […]

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Maternal and perinatal outcomes following pre-Delta, Delta, and Omicron SARS-CoV-2 variants infection among unvaccinated pregnant women

Researchers affiliated with the French and Swiss Covi-Preg registry, led by ENTIS members from the Swiss Teratology Information Service, have published a prospective cohort study describing the maternal and perinatal outcomes among unvaccinated pregnant women that tested positive for SARS-CoV-2 during the pre-Delta, Delta, and Omicron periods. More information can be found here.

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No increased risk of ADHD following benzodiazepine/z-drug hypnotic use in pregnancy

Researchers affiliated to the PharmacoEpidemiology and Drug Safety Research Group at the University of Oslo, led by ENTIS member Professor Hedvig Nordeng, have published a large comparative cohort study investigating childhood ADHD risks following maternal benzodiazepine/z-drug hypnotic use in pregnancy. The full study sample consisted of more than 82,000 singleton pregnancies, with 681 offspring exposed to benzodiazepines or z-drug hypnotics […]

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