Category: News

ENTIS affiliated researchers from the Centre Regional de Pharmacovigilance, Assistance Publique-Hopitaux de Paris (Paris-COCHIN) have analysed the spontaneous reports of gestational dolutegravir exposure and neural tube defects in the WHO worldwide pharmacovigilance database (VigiBase). More information here. Photo by freestocks.org on Unsplash

Published in the Motherisk International Journal, this knowledge summary provides a useful overview of the fetal and infant risks following maternal exposure to hydroxychloroquine in pregnancy and breastfeeding. More information is available here. Photo by The-Lore.com on Unsplash

Guidance for healthcare professionals on managing coronavirus (COVID-19) infection in pregnancy has been jointly published by the UK Royal College of Obstetricians and Gynaecologists, Royal College of Midwives and Royal College of Paediatrics and Child Health, with input from the Royal College of Anaesthetists, Public Health England and Health Protection Scotland. The updates included in these guidelines reflect recent changes […]

ENTIS colleagues from the Clinical Pharmacology Unit at Shamir Medical Center (Assaf Harofeh) in the Sackler Faculty of Medicine, Tel-Aviv, have published a helpful summary of what is known about the fetal, neonatal and maternal risks of infection with the Corona virus. The summary was published here in the Motherisk International Journal. Photo by CDC on Unsplash

Lead author of the study and ENTIS member Professor Per Damkier from the Department of Clinical Biochemistry and Pharmacology, Odense University Hospital, Denmark, stated that there appears to be about a 3-fold increased risk – while we have a relatively small number of exposed and outcomes (N=49; 6 major malformations), and hence a low precision – the signal is strong […]

Researchers from the University of South Florida have published a systematic review and meta-analysis investigating the adverse pregnancy outcome risks associated with abnormal 1-h 50-g glucose challenge test (GCT) followed by a normal 3-h 100-g glucose tolerance test (GTT). More information can be found here. Photo by Sharon McCutcheon on Unsplash

Researchers from the University of Pittsburgh, USA, and McGill University in Canada have published a study which suggests ondansetron use in the first trimester may be associated with an increased risk of ventricular septal defect. More information can be found here. Image by mmmCCC from Pixabay

A study has been published in the British Journal of General Practice which has attempted to evaluate the efficacy of an electronic patient decision making aid on antidepressant use in pregnancy. More information can be found here. Photo by Javier Allegue Barros on Unsplash

Researchers from the National Birth Defects Prevention Study have published a study which has attempted to estimate the risk of stillbirth (fetal death at 20 weeks of gestation or more) associated with specific birth defects. More information can be found here. Photo by Cassidy Rowell on Unsplash

Researchers from the National Birth Defects Prevention Study have published data collected between 1997 and 2011 investigating birth defect risks following maternal atypical antipsychotic use in pregnancy. More information can be found here. Photo by Hal Gatewood on Unsplash