New study investigates the risk of severe cardiac malformation following antidepressant use

Researchers from Aarhus University Hospital have conducted a population-based linkage of national administrative healthcare utilisation datasets to assess the risk of severe cardiac malformation following maternal first trimester antidepressant use. Interesting findings were described for the venlafaxine exposed cohort. Further information can be found here. Photo by Nastya Dulhiier on Unsplash

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Neonatal outcomes following maternal SARS-CoV-2 infection in pregnancy

Researchers from 11 academic or community hospitals in Massachusetts have published the results of a multi-centre cohort study describing the clinical outcomes of neonates born to mothers who tested positive for CV-19 in pregnancy, and the clinical and sociodemographic factors associated with positive neonatal test results. More information can be found here. Photo by Peter Oslanec on Unsplash

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Systematic review and meta-analysis quantifies the risk of birth defects following exposure to antithyroid drugs

Researchers from the University of Dundee, University of South Denmark and the University of Oslo (ENTIS Associate Member Prof Hedvig Nordeng) have collaborated on a meta-analysis examining malformation risks following maternal antithyroid drug use, calculating absolute risks for each of the different medication exposure groups. More information can be found here. Photo by Olga DeLawrence on Unsplash

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Vaccine willingness and impact of the COVID-19 pandemic on women’s perinatal experiences

Collaborators from ENTIS and affiliated organisations have published the results of a web-based survey investigating vaccine willingness among pregnant and breastfeeding women, and how the first wave of the COVID-19 pandemic impacted women’s perinatal experiences. This multinational survey was promoted in Ireland, Norway, Switzerland, the Netherlands, and the UK between 16 June and 14 July 2020, and identified considerable vaccine […]

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Observational cohort study of domperidone use in pregnancy

Researchers from the Japan Drug Information Institute in Pregnancy, a member of the ENTIS network, have recently published an observational cohort study where they compared the proportion of infants with major malformations between the infants of born to women taking domperidone (n=519) and non-teratogenic drugs during the first trimester of pregnancy. More information can be found here. Photo by Brett Jordan on Unsplash

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