Case report of elexacaftor, tezacaftor, ivacaftor combination in pregnancy

Researchers from the Sapienza University Working Group on Cystic Fibrosis in Pregnancy have published a case report on the outcome of pregnancy in a woman treated with elexacaftor, tezacaftor, ivacaftor combination during the second and third trimester of pregnancy (following discontinuation in the first trimester). More information available here. Photo by Mockup Graphics on Unsplash

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No association between leukotriene-receptor antagonist use in pregnancy and ADHD, ASD or Tourette Syndrome in the offspring

Researchers affiliated to the National Health Research Institutes in Taiwan have published a large population-based cohort study investigating the risk of ADHD, ASD or Tourette Syndrome following maternal leukotriene-receptor antagonists use in pregnancy. Further information is available here. Photo by Robina Weermeijer on Unsplash

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Neurodevelopmental outcome of children exposed to pravastatin in utero

Researchers from the Eunice Kennedy Shriver National Institute of Child Health and Human Development-Obstetrics Fetal Pharmacology Research Centers Network have conducted a long-term follow-up study to determine the impact pravastatin treatment in pregnant women at high risk of preeclampsia may have on child health, growth, and neurodevelopment. The results of this small study, although limited by the trial’s sample size […]

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ConcePTION Project: Communication toolkit launch – 15th March

Communication experts from the IMI ConcePTION project have produced a toolkit will allow organisations with limited resources to design communication campaigns to stimulate reporting of medicine use during pregnancy and breastfeeding to appropriate organisations. ENTIS members are invited to join the online launch of this toolkit on 15th March, 1500-1600 Central European Time (CET). For more information about the toolkit, […]

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Limited evidence of a link between acetaminophen (paracetamol) and autism or ADHD

FactCheck.org have published an article on the interpretation of the available evidence surrounding autism and ADHD risks in children exposed to acetaminophen (paracetamol) in utero. The article concludes that there is currently no strong evidence that acetaminophen use during pregnancy causes autism or ADHD in children, and that experts continue to recommend use of the drug during pregnancy when necessary […]

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Pregnancy and birth related experiences of postpartum women during the third wave of the COVID-19 pandemic

Researchers affiliated to the ENTIS network, led by Professor Hedvig Nordeng (University of Oslo) and Dr Michael Ceulemans (KU Leuven and Teratology Information Service Lareb), have published the results of a pan-European online questionnaire investigating pregnancy and birth related experiences of women during the third wave of the COVID-19 pandemic. More information can be found here. Photo by Alexander Grey […]

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Systematic review and meta-analysis of malformation risk following maternal metformin use in pregnancy

Researchers, including several ENTIS members and Swiss Teratology Information Service colleagues, have published a systematic review and meta-analysis of major congenital malformation risk after first-trimester exposure to metformin in women with PCOS and pre-gestational diabetes mellitus. More information can be found here. Photo by Mae Mu on Unsplash

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