Recent ENTIS study investigates the pregnancy outcomes after pregabalin exposure

A collaborative ENTIS study published in¬†Neurology¬†found an increased frequency of major malformations following exposure to pregabalin during the first trimester of pregnancy. Eight member centers of the European Network for Teratovigilance Information Services (ENTIS) conducted a study, which aimed at recording the incidence of malformations after pregabalin use during the first trimester of pregnancy [1]. Pregabalin, an anti-seizure drug, is […]

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News from the ENTIS-ISoP-NFIF Education Course and the 27th Annual ENTIS Conference 2016

The European Network of Teratology Information Services (ENTIS) in association with the International Society of Pharmacovigilance (ISOP) and the Norwegian PhD School of Pharmacy (NFIF) recently provided an education course entitled Risk Assessment of Drug Use During Pregnancy and Lactation, which was delivered in the headquarters of the Berlin-Brandenburg Academy of Sciences and Humanities in Berlin, Germany. The two day […]

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Zika virus, a new infectious teratogen? Alarming observations from Brazil

Zika virus and microcephaly in Brazil The Zika virus epidemic started in Brazil in May 2015, and by end of November more than 1,200 cases of microcephaly have been reported in Brazil during 2015, reaching a prevalence of 99.7:100,000 in live born infants, compared to the background annual prevalence of 5.5:100,000. The Zika virus disease is a mosquito-borne (Aedes species) […]

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