Category: study

Antipsychotics in Pregnancy: Large Cohort Study from the US Investigates Risk for Congenital Malformations

antipsychotics, major congenital malformations, News, study

In August 2016 JAMA Psychiatry published the results of a large pharmacoepidemiological cohort study by Krista Huybrechts et al., examining the risk for congenital malformations overall as well as cardiac malformations associated with first-trimester exposure to antipsychotics. While previous studies documented the outcome of several hundred exposed pregnancies at most, this study cohort included a nationwide sample of more than […]

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Recent ENTIS study investigates the pregnancy outcomes after pregabalin exposure

drug use in pregnancy, ENTIS News, ENTIS studies, study

A collaborative ENTIS study published in Neurology found an increased frequency of major malformations following exposure to pregabalin during the first trimester of pregnancy. Eight member centers of the European Network for Teratovigilance Information Services (ENTIS) conducted a study, which aimed at recording the incidence of malformations after pregabalin use during the first trimester of pregnancy [1]. Pregabalin, an anti-seizure drug, is […]

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