Antipsychotics in Pregnancy: Large Cohort Study from the US Investigates Risk for Congenital Malformations

In August 2016 JAMA Psychiatry published the results of a large pharmacoepidemiological cohort study by Krista Huybrechts et al., examining the risk for congenital malformations overall as well as cardiac malformations associated with first-trimester exposure to antipsychotics. While previous studies documented the outcome of several hundred exposed pregnancies at most, this study cohort included a nationwide sample of more than […]

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