Interim results have been published using data collected in the Biogen Multiple Sclerosis Pregnancy Exposure Registry. This latest study provides safety data for oral delayed-release dimethyl fumarate. More information can be found here. Photo by Robina Weermeijer on Unsplash
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Researchers from the University of Copenhagen and Copenhagen University Hospital have published a large population-based observational study investigating the safety of gestational duloxetine use. The study was conducted using data from registers in Sweden and Denmark, and provided reassuring results regarding major congenital malformation and stillbirth risks. More information can be found here.
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Researchers from Aalborg University have published a national cohort study investigating the risk of adverse pregnancy outcomes following first trimester anticoagulant exposure. More information can be found here.
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Researchers from Toulouse University have utilised the EFEMERIS database (Haute-Garonne, France) to provide safety data regarding the safety of metopimazine use in pregnancy (an anti-emetic licensed in France). More information can be found here.
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Researchers from the OTIS Collaborative Research Group have conducted a prospective study of birth outcomes among 279 women who have taken hydroxycholoroquine in pregnancy. More details can be found here. Photo by Christina Victoria Craft on Unsplash
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An interesting case report has described syncytiotrophoblasts as a major cellular target for SARS-CoV-2 infection of the placenta, and suggested that the possible stillbirth risks of placentotropic SARS-CoV-2 may be related to hampered maternal and/or fetal perfusion of the placenta. More information can be found here. Photo by João Paulo de Souza Oliveira on Unsplash
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A recent “consensus statement” review article published in Nature Reviews Endocrinology concluded that there is a growing body of evidence supporting the hypothesis that in utero exposure to paracetamol (or acetaminophen, APAP) impacts fetal development. This paper has been widely cited by national media organisations, some of which reported the findings in an alarming manner. ENTIS holds the position that […]
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Ab updated overview of the impact of COVID-19 in pregnancy has recently been published in the American Journal of Obstetrics and Gynaecology. More information can be found here.
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Researchers from the Department of Obstetrics and Gynecology and Department of Paediatrics at New York University Langone Health have published a small cohort of COVID-19 vaccinated pregnancies. More information can be found here.
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Researchers affiliated to the National Center for Birth Defect Monitoring of China have published a protocol describing a new multi-centre teratogen surveillance network in China. The surveillance system will combine pregnancy health records from numerous hospital sites to collect data on gestational medication use and pregnancy outcomes. More information can be found here. Photo by Samuel Scalzo on Unsplash
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