Category: News

A collaboration of ENTIS affiliated researchers led by Dr Kim Dao and Dr Ursula Winterfeld from Swiss Teratogen Information Service and Clinical Pharmacology Service, have published a comparative cohort study of the reproductive safety of trazadone use in early pregnancy. More information can be found here. Photo by Gregory Pappas on Unsplash

ENTIS affiliated researchers from the UK, Denmark and Israel have published a literature review and critical appraisal which explores whether recent SmPC updates applied to some pregabalin products are justified, and provides clarity on the risk-benefit balance for pregabalin use in early pregnancy. This publication was developed after the ENTIS Board and Scientific Committee submitted an official communication to the EMA […]

Researchers from the EUROlinkCAT project have published the results of a survey investigating parental satisfaction with information received about their child’s congenital anomaly. More details can be found here. Photo by sofatutor on Unsplash

Researchers from the University of California, San Diego, Mother-to-Baby research programme have published a study indicating that NSAID use in the first trimester may be associated with an increased risk of small for gestational age. More information can be found here. Photo by Patricia Prudente on Unsplash

A collaborative of researchers from Radboud University Medical Center, the Netherlands Pharmacovigilance Centre Lareb and Maastricht University, led by ENTIS associate member Dr Marleen van Gelder, have published a prospective comparative cohort study investigating preeclampsia risk among women exposed to calcium-based antacids and PPIs during pregnancy. More information can be found here. Photo by Mufid Majnun on Unsplash

Researchers affiliated to the US-based ribavirin pregnancy registry have published the final update of results describing the outcomes of 280 exposed pregnancies. More information can be found here. Photo by julien Tromeur on Unsplash

Researchers from the IMI ConcePTION project have published an inventory of European data sources for use in pharmacoepidemiologic studies investigating neurodevelopment following maternal medication exposure. More information can be found here. Photo by luis arias on Unsplash

Researchers from the University of Sydney and the Mothersafe teratology information service have published a descriptive analysis of clinical enquiries received by the service in the last 20 years. More information can be found here. Photo by Caleb Russell on Unsplash

A collaborative of researchers from Harvard University, Stanford University, Northwestern University (Chicago), University of Pittsburgh, and Brown University have published a large observational cohort study nested in the Medicaid Analytic eXtract and the IBM MarketScan Research Database investigating associations between antidepressant use in pregnancy and neurodevelopmental outcomes in children. The study results suggested up to a doubling in risk of […]

Researchers from an Italian network of 29 MS treatment centres have published a study comparing maternal MS and pregnancy outcomes between those who discontinued natalizumab treatment prior to pregnancy, those who discontinued use in the first trimester, and those who continued use throughout pregnancy. More information can be found here.