Category: News

Landmarking is a statistical methodology which may be able to serve as a an alternative to multistate modelling for the analysis of left-truncated competing risk data. Researchers affiliated with the Berlin TIS (Embryotox Center of Clinical Teratology and Drug Safety in Pregnancy) have published a demonstration of the analytical technique to examine elective termination and spontaneous abortion risks among fluoroquinolone-exposed […]

Norwegian and Taiwanese researchers have published a cross national, population-based cohort study investigating malformation risks following paternal metformin use. The findings suggest that paternal use of metformin is not associated with congenital malformation in the offspring, including organ specific malformations. More information is available here. Photo by Mae Mu on Unsplash

Brazilian researchers have published a case series of newborns with microcephaly in Brazil in which they discuss vertical transmission of Oropouche virus (OROV) as the possible aetiological cause. The authors of the case series conclude that the evidence they present does not confirm vertical transmission or congenital malformations due to OROV disease in pregnancy, but call for priority action in […]

Researchers from the Department of Pharmacology at the All India Institute of Medical Sciences have published a systematic review and meta-analysis investigating the risk of congenital anomalies in following exposure to dolutegravir-based-regimens in pregnancy. More information is available here. Photo by National Institute of Allergy and Infectious Diseases on Unsplash

Oropouche virus (OROV) is an arbovirus endemic in Latin America and the Caribbean. A recent outbreak of the virus has been associated with reports of pregnant women infected with OROV who have had miscarriages and stillborn fetuses with placental, umbilical blood and fetal somatic organ samples that were RT-PCR positive for OROV and negative for other arboviruses. Travelers with Oropouche […]

ENTIS members from the University of Oslo have developed a novel algorithm to more completely detect and date early pregnancy outcomes (i.e., miscarriages, elective terminations, ectopic pregnancies, molar pregnancies, stillbirths, and live births) using diagnostic codes from primary and secondary care registries to complement information from the national birth registry. More information can be found here. Photo by Luke Chesser […]