Researchers from the U.S. Centers for Disease Control and Prevention (Atlanta, Georgia) have published a study investigating patterns of alcohol consumption in pregnancy relative to the implementation of legal nonmedical cannabis retail sales (details here). Other notable publications include: A narrative review of neurodevelopmental outcomes among children born to women infected with SARS-CoV-2 during pregnancy (details here). A study of […]
» Read more
Researchers affiliated with the University of Hong Kong have published an observational cohort study examining prenatal psychotropic exposure and pregnancy outcomes. The dataset includes 500,000 births, with more than 7,000 psychotropic exposures. More information is available here. Photo by Melany @ tuinfosalud.com on Unsplash
» Read more
The team at TIS Berlin (Pharmakovigilanz- und Beratungszentrum für Embryonaltoxikologie) have published the results of their long-term project investigating whether an extended follow-up period improves the detection of birth defects. The results of the study are published here, and an open access PDF was also kindly provided by the study authors. Photo by Christian Bowen on Unsplash
» Read more
A sub-study within the ConcePTION project led by researchers from the Swiss Teratology Information Service and the Department of Pharmaceutical and Pharmacological Sciences at KU Leuven in Belgium has resulted in the development of a clinical decision tree to guide researchers in selecting the most appropriate methodological approach for evaluating the safety of medication during breastfeeding. More details about the about […]
» Read more
The American College of Obstetricians and Gynaecologists have issued a statement describing the benefits of ensuring pregnant women have adequate access to SSRI antidepressants during pregnancy. The statement (available here) was issued in response to a panel discussion held by the U.S. Food and Drug Administration (FDA) which aired on Monday 21st July.
» Read more
A new collaboration between the Teratology Information Service CRAT (Centre de Reference sur les Agents Tératogènes) and the French Network of Pharmacovigilance Centres has produced the largest to date prospective case series of CFTR modulator exposed pregnancies. The article has been published in the Journal of Cystic Fibrosis, and more details are available here. Photo by Robina Weermeijer on Unsplash
» Read more
Researchers from Izmir TIS (Izmir Katip Celebi University Teratology Information Center) have published a case series of 45 pregnancies in women who used feviparivir, More information is available here. Photo by Simon Kadula on Unsplash
» Read more
Recent research conducted at TIS Paris Cochin includes: A comprehensive analysis into the safety of ifosfamide in pregnancy, including a review of literature cases, cases in the French pharmacovigilance database, and a disproportionality analysis of Vigibase. A comparative cohort study of pregnancy outcomes following CFTR modulator use in pregnancy. A nationwide cohort study investigating the impact of clomiphene citrate on […]
» Read more
Researchers from Seoul National University (Republic of Korea), have published a population-based, propensity score matched cohort study investigating fetal and childhood outcomes following maternal statin use in pregnancy. More information is available here.
» Read more
A collaborative group of Brazilian researchers has published a systematic review and meta analysis of autism spectrum disorder risk following maternal antiseizure medication (ASM) use in pregnancy. The updated analysis provides pooled risk estimates for specific ASMs, demonstrating increased risks for carbamazepine, valproate and oxcarbazepine. More information can be found here.
» Read more